top of page
CarlaOliveiraLab
Laboratory of Post-Transcriptional Control of Gene Expression
Institute of Chemistry
Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6
Institute of Chemistry
1/8
The ribosome assembly factor Nop53 has a structural role in the formation of nuclear pre-60S intermediates, affecting late maturation events - Bagatelli et al., 2021. Nucleic acids research.
Crystal structure of the Pyrococcus abyssi exosome RNase PH complexed with a single-stranded 10-merpoly(A) RNA - Navarro et al., 2008. J Biol Chem.
The ribosome assembly factor Nop53 controls association of the RNA exosome with pre-60S particles in yeast - Cepeda et al., 2019. J Biol Chem.
This work was reported by the Department of Biochemistry from IQ-USP.
Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae - Gonzales-Zubiate et al., 2017. J Biol Chem.
This work was selected in this special JBC issue.
"Para a professora Carla Columbano de Oliveira, do Instituto de Química (IQ) da USP, não existe uma diferença clara entre o que é pesquisa básica e o que é pesquisa aplicada. Se um cientista não souber o que acontece na célula, argumenta ela, não há maneira de aplicar. E prossegue: 'é uma questão de tempo. Se eu não sei o que a proteína faz, como eu vou desenvolver um medicamento?'".
Publicado: 06/09/2013
The research is financially supported by FAPESP, CNPq and CAPES grants.
Our current financial grant:
bottom of page